HEAIDS implements the following programmes and projects in the higher education and training sector:

First Things First (FTF) is HEAIDS flagship programme that provides HIV/TB and STI testing and screening services through mobile clinics that are accessible to universities and colleges on a regular basis. First Things First also allows for provision of general health and wellness services, including non-communicable diseases. To mobilise students to get to know their status and provide platforms for dialogues, peer educators are trained across the country. Free scented condoms are provided by the National Department of Health.

The women health and men health programmes further support the objectives of First Things First through the provision of cancer screenings and voluntary medical male circumcision, as well as women’s and men’s empowerment programmes.

HEAIDS Curriculum development programme aims at capacitating academic staff across disciplines to appropriately integrate and address HIV/AIDS and it’s intersectionalties in curricular at universities and TVET colleges. Since 2018 HEAIDS focuses on the training of Life Orientation lecturers in the area of sexual and reproductive health and rights, gender diversity and disability.

The innovative Future Beats project is HEAIDS renowned behaviour change communication programme that capacitates young radio journalists in addressing HIV and social drivers of the pandemic through radio and social media. The programme currently reaches 670,000 young radio listeners in six provinces of South Africa.

Furthermore, HEAIDS MSM and LGBTI programme promotes an enabling environment and access to appropriate HIV treatment, care and prevention services for Men who have Sex with Men (MSM) and Lesbian, Gay, Bisexual, Transgender and Intersexed (LGBTI) persons.

HEAIDS Alcohol and drug abuse prevention programme provides a primary prevention response to substance abuse as an HIV risk factor. It involves risk screenings and brief interventions using digital media, health clinics, trained professionals and lay counsellors.